What happens @ PathCare?
Have a look behind the scenes to see how patient specimen
flow is regulated in our laboratory system.
- Allergy 
- Antimicrobials & infection 
- Autoimmune 
- Chemical Pathology 
- Endocrinology 
- Epidemiology 
- Gastrointestinal 
- Genetic Analysis 
- Genitourinary 
- Haematology 
- HIV/TB 
- Infectious Diseases 
- Neurology 
- Obstetric and Neonatal care 
- Oncology 
- Ophthalmology 
- Respiratory 
- Serology 
- Virology 
The autoimmune liver diseases include the triad of Autoimmune Hepatitis (AIH), Primary Biliary Cholangitis (PBC) and Primary Sclerosing Cholangitis (PSC). These conditions represent perhaps only 5% of all liver diseases, although the true prevalence in South-Africa is uncertain. Autoimmune liver conditions should be considered as a diagnosis after viral, metabolic and drug induced liver injuries have been excluded.
Genetic counselling provides people with information about genetics and risks, the benefits, possibilities and limitations of genetic testing, potential outcomes of testing and management options.
Your doctor/genetic counsellor has ordered an Invitae genetic test for you or your child through PathCare. invitae Laboratory, based in the USA, will be performing your testing and PathCare is here to coordinate the process. The attached information will guide you through the process.
The porphyrias arise from enzyme defects in the haem biosynthetic pathway. Accumulation of the precursors (ALA and PBG) lead to acute neurovisceral attacks, marked by severe abdominal pain and autonomic neuropathy, which may progress to a potentially fatal motor neuropathy. Accumulation of the porphyrins lead to photocutaneous sensitivity, which presents with skin fragility, blistering and erosions in sun-exposed areas.
A sweat test measures the amount of salt in the sweat of the patient. It is used to diagnose cystic fibrosis (CF). Patients with CF have high levels of salt in their sweat. CF is a disease that causes mucus build-up in the lungs and other organs. It damages the lungs and makes it
difficult to breathe.
Key considerations:A key issue is the small volume of sample that is available. It is not feasible to perform all tests on all samples whilst maintaining optimum sensitivity.Therefore, it is the clinician's responsibility to prioritise testing for each...
Below we present the PathCare susceptibility data for common community-acquired respiratory tract organisms isolated from lower respiratory tract samples of patients in the Eastern Cape during 2018. As this data reflects the susceptibility of all isolates,...
E. coli is the major aerobic commensal organism in the gut and only causes disease following some disruption of gut, e.g. after penetrating injury. However, a number of E. coli strains or pathotypes possessing particular sets of virulence factors are...
South Africa carries a heavy influenza burden with more than 12000 deaths each year due to influenza associated severe acute respiratory illness. The most effective strategy to prevent influenza is vaccination.VaccinationAdminister the vaccine each year...