Approximately 10% of all colorectal cancers (CRC) are hereditary.  Patients who carry a pathogenic germline variant in a CRC-related gene have an increased risk to develop CRC, as well as other cancers.  Genetic testing may confirm a diagnosis and help guide treatment and management decisions.  Identification of a disease-causing variant would also guide screening, testing and early diagnosis of at-risk relatives.

Genetic testing for hereditary colorectal and endometrial cancer

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