Testing for respiratory pathogens using comprehensive multiplex molecular panels have become a valuable diagnostic tool to assist in early identification of causative organisms. Appropriate use supports timely and directed antimicrobial therapy, especially for organisms that cannot be routinely cultured (e.g Mycoplasma, Legionella, Chlamydophila, Bordetella, and viruses); decreases in-hospital admission rate, length of hospital stay, and also assists in antimicrobial stewardship by avoiding the use of empiric antimicrobial agents
Immune-mediated diabetes is characterized by the presence of circulating specific antibodies against the pancreatic islets such as glutamic acid decarboxylase autoantibodies (GADA), islet antigen-2 autoantibodies (IA-2A), or zinc transporter-8 autoantibodies (ZnT8A).
The presence of viral RNA in respiratory samples is critical information in the diagnosis of an acute SARS-COV-2 infection. The real-time reverse transcription-polymerase chain reaction (RT-PCR) detects these pieces of RNA. But RT-PCR is a poor test of cure. The presence of RNA does not imply the presence of infectious or replication-competent virus.