Knowledge Hub
What happens @ PathCare?
Have a look behind the scenes to see how patient specimen
flow is regulated in our laboratory system.
Categories:
- Allergy [1]
- Antimicrobials & infection [3]
- Autoimmune [1]
- Chemical Pathology [13]
- Endocrinology [1]
- Epidemiology [3]
- Gastrointestinal [2]
- Genetic Analysis [12]
- Genitourinary [2]
- Haematology [9]
- HIV/TB [3]
- Infectious Diseases [9]
- Neurology [4]
- Obstetric and Neonatal care [6]
- Oncology [5]
- Ophthalmology [1]
- Respiratory [2]
- Serology [3]
- Virology [18]
Covid-19 associated pulmonary aspergillosis (CAPA)
In individuals with co-morbidities, defective immune responses to SARS-CoV-2 may allow unrestricted viral replication which elicits hyperinflammation and severe complications such as acute respiratory distress syndrome (ARDS).
COVID-19 resulting in ARDS has recently emerged as an important disease that predisposes patients to secondary pulmonary aspergillosis.
Advances in molecular oncology: Liquid biopsy for non-small cell lung cancer
In recent years, liquid biopsies have emerged as a promising tool in the fields of molecular oncology and precision medicine. Liquid biopsy methodology typically analyses genomic DNA isolated from circulating tumour cells (CTCs) or circulating cell-free tumour DNA (cfDNA/ctDNA) in a peripheral blood sample, to gain insight into the genomic profile of the patients’ tumour.
Polymyxin guidelines
Due to a rapid increase in serious infections related to especially carbapenemase producing Enterobacterales, the clinical use of the polymyxin antibiotics colistin (polymyxin E), and polymyxin B has recently resurged as salvage therapy for otherwise untreatable Gram-negative infections.
Your newborn baby’s screening test brochure
Newborn screening is a process where infants are screened for specific conditions shortly after birth. These conditions may not always be clinically evident in the newborn period.
Newborn Screening: Clinician and Parent support service
Newborn screening (NBS) is a form of preventative health care and entails the process of screening infants for specific genetic conditions in the first few days of their life.
Products of Conception Chromosome screening
Chromosomal aneuploidies (abnormal number of chromosomes) are the most common of first trimester miscarriage, accounting for more than 50% of spontaneous abortions.
Family ancestry in the context of diagnostic genetic testing
Genetics is an evolving field, and even though technology has improved in order to identify more disease-causing genetic variants, current laboratory testing strategies still have significant limitations.
Hepatitis E: Is this Virus Relevant in Southern Africa?
A fairly recent article on the nationwide outbreak of Hepatitis E (HEV) in informal settlements in Namibia as well as the recent academic interest in this previously mostly ignored virus, prompted this EduPath.
Serological assays for SARS-COV-2 vaccine responses
PathCare has introduced an antibody test that is capable of detecting antibodies directed against the SARS-CoV-2 spike (“S”) protein, induced by SARS-CoV-2 vaccines or by natural infection