There is currently a global stock shortage of Betanoid (betamethasone) tablets. Betanoid is used in the Dexamethasone Suppression Test for screening of Cushing’s Syndrome. PathCare will, until further notice, be unable to supply patients with Betanoid tablets. ...
Knowledge Hub
Update: BioFire Filmarray Syndromic Panels
Testing for respiratory pathogens using comprehensive multiplex molecular panels has become a valuable diagnostic tool to assist in early identification of causative organisms. Appropriate use supports timely and directed antimicrobial therapy, especially for...
Respiratory Virus Statistics: Jan – April 2022
The National Institute for Communicable Diseases declared the start of the respiratory syncytial virus (RSV) season in week 7 (week ending 20 February) and the positivity rate has continued to increase through March and April.Circulation of adenovirus, parainfluenza...
Typhoid/Salmonella Testing
Enteric fever includes typhoid fever (an infection caused by Salmonella enterica serotype Typhi) and paratyphoid fever (infections caused by Salmonella enterica subspecies enterica serotypes Paratyphi A, B or rarely, C) Paratyphoid fever isclinically indistinguishable...
Primary Aldosteronism: An Under-Recognised Problem
Primary aldosteronism (PA), also known as Conn's syndrome, is common and has a significantly higher cardiovascular risk profile than sex-, age-, and BP-matched patients with essential hypertension. PA is now considered a major public health issue, which requires a...
Indeterminate COVID results
The polymerase chain reaction (PCR) test for the detection of SARS-CoV-2 in respiratory specimens is an essential tool in screening and diagnosing COVID-191. Clinical virology laboratories often make use of a diverse repertoire of testing platforms with varying...
Hyperuricaemia and Gout: Important Lessons to be Learnt
Gout is a common clinical disease and, furthermore, it is readily treatable and managed by the long-term use of urate lowering medication. Gout, the clinical syndrome, needs to be distinguished from hyperuricaemia which refers to the increased levels of serum urate. ...
Frequently asked questions: SARS-CoV-2 B.1.1.529/Omicron variant
On 26 November 2021 the WHO designated the new SARS-CoV-2 lineage B.1.1.529, now named Omicron, a variant of concern. Much is still unknown about Omicron and it is expected that the variant’s real world impact will become clearer over the next weeks. What is Omicron?...
Covid-19 associated pulmonary aspergillosis (CAPA)
COVID-19 and ARDS In individuals with co-morbidities, defective immune responses to SARS-CoV-2 may allow unrestricted viral replication which elicits hyperinflammation and severe complications such as acute respiratory distress syndrome (ARDS).COVID-19 resulting in...
Advances in molecular oncology: Liquid biopsy for non-small cell lung cancer
In recent years, liquid biopsies have emerged as a promising tool in the fields of molecular oncology and precision medicine. Liquid biopsy methodology typically analyses genomic DNA isolated from circulating tumour cells (CTCs) or circulating cell-free tumour DNA...
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