Porphyria Testing Update

The porphyrias arise from enzyme defects in the haem biosynthetic pathway. Accumulation of the precursors (ALA and PBG) lead to acute neurovisceral attacks, marked by severe abdominal pain and autonomic neuropathy, which may progress to a potentially fatal motor...

β-Hydroxybutyrate

Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus, and consists of the biochemical triad of ketosis, hyperglycaemia and acidaemia. DKA usually occurs as a result of an absolute or relative insulin deficiency and an increase in...

Serum Free Light Chains

Serum Free Light Chains – An Essential Test in Myeloma. Multiple Myeloma (MM) is the 2nd most common haematological malignancy.  Serum free light chain (s-FLC) testing now forms an integral part of the management of MM. The serum levels of free light chains...

Apolipoprotein B & A1

The association between cardiovascular disease (CVD) risk and plasma low density lipoprotein-cholesterol (LDL-c) level is indisputable.  Accordingly, all screening and therapeutic guidelines are based on total cholesterol (TC) or LDL-c levels. Apolipoprotein B &...

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