Feb 2, 2023 | Knowledge Hub
During the month of January 2023, Pathcare confirmed a number of Rickettsia infections although both serological confirmation as well as PCR confirmation have significant limitations. The two common spotted fever diseases in Southern Africa are boutonneuse fever-like...
Jan 31, 2023 | Knowledge Hub
Measles morbillivirus (MV) is one of the most contagious human pathogens. MV infection occurs worldwide, sporadically or through outbreaks, such as the current outbreak in South Africa. Since late 2022, MV outbreaks have been declared in 5 provinces, namely,...
Jan 30, 2023 | Knowledge Hub
DPYD, the gene encoding dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme for fluoropyrimidine catabolism. In the context of 5-fluorouracil, four decreased function DPYD variants are of primary relevance due to their population frequency and...
Jan 19, 2023 | Infectious Diseases, Knowledge Hub
INFLUENZA, RESPIRATORY SYNCYTIAL VIRUS AND SARS-COV-2 Influenza A, influenza B and respiratory syncytial virus (RSV) returned to the characteristic seasonal circulation (Figure 1), having shown atypical patterns in 2020 and 2021. The influenza season showed a biphasic...
Nov 30, 2022 | Infectious Diseases, Knowledge Hub
The recent COVID-19 pandemic renewed the focus of the role of vaccination in the prevention of infection across all ages and in all communities. Apart from reducing infectious episodes in individual patients, vaccination is an often-overlooked strategy to also combat...
