We are pleased to announce the launch our Next Generation Sequencing panel for Solid tumours (Oncomine Focus assay). This has been done in an attempt to improve and streamline our molecular pathology testing offering. As opposed to testing for single gene...
Knowledge Hub
Minimum repeat intervals for procalcitonin (PCT) and C-reactive protein (CRP)
Procalcitonin (PCT) is a 116 amino acid peptide precursor of calcitonin. In the absence of infection, it is produced at very low levels in a few highly selected tissues. However, at the onset of infection bacterial factors and host inflammatory cytokines...
Laboratory investigations after occupational or non-occupational exposure to HIV and other blood borne pathogens
Southern Africa has a very high background prevalence of HIV infection, making exposure risk both inside and outside the occupational setting high. The approach to occupational, sexual and other forms of exposure (bites, assaults, trauma, injecting drug...
ESR on the iSED
Alternate or modified Westergren methods to measure erythrocyte sedimentation rate (ESR) have been adopted by laboratories worldwide. These methods offer reduction in analysis time and improved operator safety. The iSED Erythrocyte Sedimentation Rate...
Hepatitis B and Pregnancy
Acute Viral Hepatitis is the most common cause of jaundice in pregnancy. HBV infection during pregnancy is usually mild, not associated with increased mortality or teratogenicity, and should not prompt consideration of termination. Acute HBV infection...
Rapid Identification of Blood Cultures
Pathcare Reference Laboratory has recently instituted a rapid blood culture ID technique where organisms from positive blood cultures can now be identified after about 4 hours from the time when the blood culture system flags the blood culture bottle as...
GIT Panel: Molecular diagnostic panel improves the diagnosis of infective diarrhoea
Although few gastrointestinal infections may require specific therapy, the quick and efficient detection of a causative agent of diarrhoea may limit unnecessary use of antimicrobials, reduce hospitalisation duration and also provide valuable information...
BioFire Meningitis/Encephalitis PCR test
PathCare offers a Meningitis/Encephalitis Multiplexed PCR test with an expanded organism profile and reduced turn-around time, detecting 14 potential central nervous system (CNS) pathogens. The ME Panel is able to detect and identify multiple bacterial,...
β-Hydroxybutyrate
Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus, and consists of the biochemical triad of ketosis, hyperglycaemia and acidaemia. DKA usually occurs as a result of an absolute or relative insulin deficiency and an...
Diagnosis of B12 and Folate Deficiency
Vitamin B12 and folate are vitamins required for normal haematopoiesis and neurologic function. They are often considered together, although folate deficiency has become exceedingly rare in individuals who are living in developed countries and...
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