Knowledge Hub

Malaria Update

Recent heavy rainfall across South Africa has led to a continued rise in Malaria cases

Respiratory Pathogen Statistics 2025 Summary

This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during 2025

Launch of Salivary Cortisol & Cortisone via LC-HRMS

PathCare will now offer simultaneous measurement of salivary cortisol and cortisone using liquid chromatography–high-resolution mass spectrometry (LC-HRMS).

MOLECULAR SUBTYPING OF ENDOMETRIAL CARCINOMA

Molecular subtyping can assist with predicting treatment outcomes and prognosis of early endometrial cancer and is recommended by the National Comprehensive Cancer Network (NCCN) guidelines.

Respiratory Pathogen Statistics September 2025

This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during September 2025

Gastro-Intestinal Pathogen Statistics

Laboratory-based data for all GIT molecular panels requested for patients at PathCare laboratories nationally, for the period June to August 2025, are presented in this report.

The value of therapeutic drug monitoring of linezolid in clinical practice

Linezolid, a synthetic oxazolidinone antibiotic, is frequently used for the treatment of serious gram-positive infections including Staphylococcus aureus and enterococci.

Respiratory Pathogen Statistics August 2025

This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during August 2025

The ABC’s of MICs: The value of MIC results in antibiotic treatment decisions

The clinical microbiology laboratory provides valuable susceptibility data that can guide the selection of antibiotic regimens for patients with infections.

With regard to Designated Service Provider (DSP) Contracts the following law is pertinent for service providers who are not a DSP:

  1. In terms of Section 59 (2) of the Medical Schemes Act 131 of 1998 the medical scheme must pay valid invoices within 30 days of receipt thereof or advise both the member and service provider of reasons why the invoice is not valid and provide the opportunity to correct the invoice.
  2. Where services are in respect of medical emergencies or involuntarily obtained services for PMB conditions, the scheme has to pay for the full cost of the services provided without deduction or co-payment or limiting the tariff amount. (Regulation 8 (1) of the Medical Schemes Act no. 131 of 1998.)
  3. DOH notice 214 of 2021 requires that a scheme pays for services provided at the same rate and in terms of the same rules as they pay their DSPs in respect of services voluntarily obtained, whether they are PMBs or not.
  4. The process followed in respect of appointing a DSP is required to be fair, equitable, transparent, competitive or cost effective as required in terms of Notice 214 of the DOH.

In summary:

  1. The law protects the patient’s choice to use their laboratory of choice, even if it is not a DSP, and the scheme is still obliged to reimburse us at the scheme rate for valid claims.
  2. This is true for PMB conditions as well as non-PMB conditions.
  3. The medical scheme must pay valid invoices within 30 days or advise both the member and service provider of reasons why the invoice is not valid and provide the opportunity to correct invoice.
  4. A scheme must pay for the services provided at a tariff not less than what they would pay a DSP.
  5. Should any patient have a valid claim rejected because we are not a DSP, we can assist.

 

Respiratory Virus Statistics: June 2022

The influenza season continued during June, with influenza A positivity rates remaining above 25% throughout the month despite a gradual weekly decline. Influenza B detection rates remained below 5%. Influenza A positive samples were mostly H1N1 strains, although H3N2 positivity increased gradually towards the end of June.

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Combined Influenza A/Influenza B/RSV/SARS-CoV-2 panels

Limited multiplex PCR panels are useful when multiple organisms causing similar clinical presentations are in circulation. Rates of RSV (respiratory syncytial virus) have increased across all provinces in recent weeks while SARS-CoV-2 rates have also increased. Influenza season characteristically starts in early June in South Africa, implying that co-circulation of these pathogens has a high likelihood of occurring.

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Respiratory Virus Statistics: May 2022

The National Institute for Communicable Diseases declared the start of the influenza season in week 17 (week ending 1 May) and influenza A positivity rates have continued to increase during May 2022, reaching 36.1% during week 22 nationally (week ending 5 June). Influenza B detection rates  remain low.

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Monkeypox Guidance for Clinicians

With the identification of cases of monkeypox in various non-endemic countries since early May 2022, heightened vigilance is required in order to contain the spread of this virus.  Monkeypox virus is transmitted by contact with infected animals or humans, or other contaminated material.

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Global shortage of Betanoid Tablets

There is currently a global stock shortage of Betanoid (betamethasone) tablets. Betanoid is used in the Dexamethasone Suppression Test for screening of Cushing’s Syndrome. PathCare will, until further notice, be unable to supply patients with Betanoid tablets.

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