The D-Dimer test will be offered on the MINI VIDAS ®.The report will state on which instrument the D-Dimer test result was obtained. On the Mini Vidas ® the test is an automated quantitative test for the immune-enzymatic determination of fibrin degradation products in...
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Flow cytometry for accurate detection and quantitation of fetal maternal haemorrhage
Transplacental or fetomaternal haemorrhage (FMH) may occur during pregnancy or at delivery and lead to immunisation to the D antigen if the mother is D negative and the baby D positive. This can result in haemolytic disease of the fetus and newborn (HDN) in subsequent...
Diagnostic Testing for Autoimmune Liver Diseases
The autoimmune liver diseases include the triad of Autoimmune Hepatitis (AIH), Primary Biliary Cholangitis (PBC) and Primary Sclerosing Cholangitis (PSC). These conditions represent perhaps only 5% of all liver diseases, although the true prevalence in South-Africa is...
Porphyria Testing Update
The porphyrias arise from enzyme defects in the haem biosynthetic pathway. Accumulation of the precursors (ALA and PBG) lead to acute neurovisceral attacks, marked by severe abdominal pain and autonomic neuropathy, which may progress to a potentially fatal motor...
Update on Laboratory testing of Ophthalmology Samples
Key considerations:A key issue is the small volume of sample that is available. It is not feasible to perform all tests on all samples whilst maintaining optimum sensitivity.Therefore, it is the clinician's responsibility to prioritise testing for each...
Eastern Cape respiratory surveillance data
Below we present the PathCare susceptibility data for common community-acquired respiratory tract organisms isolated from lower respiratory tract samples of patients in the Eastern Cape during 2018. As this data reflects the susceptibility of all isolates,...
A guide to diarrheagenic E.coli
E. coli is the major aerobic commensal organism in the gut and only causes disease following some disruption of gut, e.g. after penetrating injury. However, a number of E. coli strains or pathotypes possessing particular sets of virulence factors are adapted to cause...
Influenza Update 2019
South Africa carries a heavy influenza burden with more than 12000 deaths each year due to influenza associated severe acute respiratory illness. The most effective strategy to prevent influenza is vaccination.VaccinationAdminister the vaccine each year because the...
Iron Deficiency Anaemia in Adults
Iron is an intriguing nutrient with many paradoxical characteristics. it is the most abundant element on our planet and yet it is hard for living organisms to access due to its very low solubility. Its ability to switch easily between the ferric and...
Solid Tumours (Oncomine Focus)
We are pleased to announce the launch our Next Generation Sequencing panel for Solid tumours (Oncomine Focus assay). This has been done in an attempt to improve and streamline our molecular pathology testing offering. As opposed to testing for single gene...
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