Bacterial vaginosis (BV) is the most common cause of vaginal discharge in women. It is characterised by a dysbiosis of the normal vaginal flora whereby a mixed bacterial flora including mixed anaerobes replaces the dominant lactobacilli. This is associated with the...
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Preventing invasive cryptococcal disease through active screening for cryptococcal antigenemia in people living with advanced HIV
Cryptococcal meningitis remains a significant cause of morbidity and mortality among people living with HIV (PLHIV), particularly in resource-limited settings. In South Africa, it is estimated that cryptococcal meningitis accounts for approximately 15% of AIDS-related...
Gastrointestinal (GIT) Pathogen Statistics
In this report we present laboratory-based data for all GIT molecular panels requested for patients at PathCare laboratories for the last quarter (October to December 2024). Graphs and data will be presented to highight the leading bacterial, viral and parasitic...
Update on Human Metapheumovirus (hMPV)
Background Recent media reports raised concerns regarding an increase in human metapneumovirus (hMPV) cases in China. This document aims to provide a summary of the current respiratory infection season in China and provide a brief overview of hMPV. Introduction In the...
Diphtheria
Four laboratory-confirmed adult cases of diphtheria, caused by Corynebacterium diphtheriae, have recently been identified in the Cape Metropole district in the Western Cape. These cases are a reminder that a reduction in vaccine coverage may lead to more cases and...
Respiratory Pathogen Statistics: 2024 Summary
This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during 2024, with additional data from December 2024. As with the monthly respiratory pathogen reports, the data is dependent on...
Respiratory Pathogen Statistics: October 2024
This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during October 2024 (epidemiological weeks 40-44). The data is dependent on submission of samples by clinicians and therefore may not be...
Gastro-intestinal pathogen statistics
In this report we present laboratory-based data for all GIT molecular panels requested for patients at PathCare laboratories for the last two quarters (March to August 2024). We have included graphs and data for bacterial, viral and parasitic causes of diarrhoea....
Respiratory pathogen statistics: September 2024
This report is a summary of the results obtained from various molecular respiratory panels performed across PathCare laboratories during September 2024 (epidemiological weeks 36-39). The data is dependent on submission of samples by clinicians and therefore may not be...
Precision Anti-PLA2R Quantification for Membranous Nephropathy
Membranous Nephropathy (MN) is among the most common causes of nephrotic syndrome in adults without diabetes. If left untreated, it can progress to kidney failure. Depending on the absence or presence of associated conditions, MN is traditionally classified as primary...
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