Knowledge Hub

 

   

   What happens @ PathCare?

   Have a look behind the scenes to see how patient specimen

   flow is regulated in our laboratory system.

Minimum repeat intervals for procalcitonin (PCT) and C-reactive protein (CRP)

Procalcitonin (PCT) is a 116 amino acid peptide precursor of calcitonin. In the absence of infection, it is produced at very low levels in a few highly selected tissues. However, at the onset of infection bacterial factors and host inflammatory cytokines...

Laboratory investigations after occupational or non-occupational exposure to HIV and other blood borne pathogens

Southern Africa has a very high background prevalence of HIV infection, making exposure risk both inside and outside the occupational setting high. The approach to occupational, sexual and other forms of exposure (bites, assaults, trauma, injecting drug...

ESR on the iSED

Alternate or modified Westergren methods to measure erythrocyte sedimentation rate (ESR) have been adopted by laboratories worldwide. These methods offer reduction in analysis time and improved operator safety. The iSED Erythrocyte Sedimentation Rate...

Hepatitis B and Pregnancy

Acute Viral Hepatitis is the most common cause of jaundice in pregnancy.  HBV infection during pregnancy is usually mild, not associated with increased mortality or teratogenicity, and should not prompt consideration of termination.  Acute HBV infection...

Rapid Identification of Blood Cultures

Pathcare Reference Laboratory has recently instituted a rapid blood culture ID technique where organisms from positive blood cultures can now be identified after about 4 hours from the time when the blood culture system flags the blood culture bottle as positive.

GIT Panel: Molecular diagnostic panel improves the diagnosis of infective diarrhoea

Although few gastrointestinal infections may require specific therapy, the quick and efficient detection of a causative agent of diarrhoea may limit unnecessary use of antimicrobials, reduce hospitalisation duration and also provide valuable information...

Breast & Ovarian Cancer: Genetic Testing

PathCare is proud to offer both in-house and international send-away genetic testing for breast and ovarian cancer.  Our molecular laboratory offers genetic testing using Sanger and Next Generation Sequencing technologies.  We pride ourselves...

Preconception Carrier Screening

PathCare offers a referral service to Invitae Laboratory in the USA.  Invitae offers an extensive genetic test menu over a broad range of clinical areas, and has recently introduced comprehensive carrier screening to their testing catalogue...

Non-Invasive Prenatal testing Q&A

PathCare offers Non-Invasive Prenatal screening.  Please see our  frequently asked questions so you can make an informed decision Non-Invasive Prenatal Screening Q&A

β-Hydroxybutyrate

Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus, and consists of the biochemical triad of ketosis, hyperglycaemia and acidaemia. DKA usually occurs as a result of an absolute or relative insulin deficiency and an...

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Syphilis

PathCare utilizes the Treponema pallidum antibody assay as a screening test for syphilis. This is in line with international reporting standards. The Treponema pallidum antibody test is an economic and reliable automated syphilis serology test. It utilizes...

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Serum Free Light Chains

Serum Free Light Chains - An Essential Test in Myeloma. Multiple Myeloma (MM) is the 2nd most common haematological malignancy.  Serum free light chain (s-FLC) testing now forms an integral part of the management of MM. The serum levels of free light...

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