Knowledge Hub

 

   

   What happens @ PathCare?

   Have a look behind the scenes to see how patient specimen

   flow is regulated in our laboratory system.

Influenza Update 2019

South Africa carries a heavy influenza burden with more than 12000 deaths each year due to influenza associated severe acute respiratory illness. The most effective strategy to prevent influenza is vaccination. Vaccination Administer the vaccine each year...

Genetic testing for hereditary colorectal and endometrial cancer

Approximately 10% of all colorectal cancers (CRC) are hereditary.  Patients who carry a pathogenic germline variant in a CRC-related gene have an increased risk to develop CRC, as well as other cancers.  Genetic testing may confirm a diagnosis and help...

Genetic testing for hereditary prostate cancer

Nearly 1 in 6 prostate cancer patients has a germline disease-causing genetic variant. A recent study in JAMA Oncology examining 3607 men with a personal history of prostate cancer has found that 17% had a germline disease-causing genetic variant.  This...

Iron Deficiency Anaemia in Adults

Iron is an intriguing nutrient with many paradoxical characteristics.  it is the most abundant element on our planet and yet it is hard for living organisms to access due to its very low solubility.  Its ability to switch easily between the ferric and...

Solid Tumours (Oncomine Focus)

We are pleased to announce the launch our Next Generation Sequencing panel for Solid tumours (Oncomine Focus assay). This has been done in an attempt to improve and streamline our molecular pathology testing offering.  As opposed to testing for single gene...

Minimum repeat intervals for procalcitonin (PCT) and C-reactive protein (CRP)

Procalcitonin (PCT) is a 116 amino acid peptide precursor of calcitonin. In the absence of infection, it is produced at very low levels in a few highly selected tissues. However, at the onset of infection bacterial factors and host inflammatory cytokines...

Laboratory investigations after occupational or non-occupational exposure to HIV and other blood borne pathogens

Southern Africa has a very high background prevalence of HIV infection, making exposure risk both inside and outside the occupational setting high. The approach to occupational, sexual and other forms of exposure (bites, assaults, trauma, injecting drug...

ESR on the iSED

Alternate or modified Westergren methods to measure erythrocyte sedimentation rate (ESR) have been adopted by laboratories worldwide. These methods offer reduction in analysis time and improved operator safety. The iSED Erythrocyte Sedimentation Rate...

Hepatitis B and Pregnancy

Acute Viral Hepatitis is the most common cause of jaundice in pregnancy.  HBV infection during pregnancy is usually mild, not associated with increased mortality or teratogenicity, and should not prompt consideration of termination.  Acute HBV infection...

Rapid Identification of Blood Cultures

Pathcare Reference Laboratory has recently instituted a rapid blood culture ID technique where organisms from positive blood cultures can now be identified after about 4 hours from the time when the blood culture system flags the blood culture bottle as positive.

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β-Hydroxybutyrate

Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus, and consists of the biochemical triad of ketosis, hyperglycaemia and acidaemia. DKA usually occurs as a result of an absolute or relative insulin deficiency and an...

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